Dapagliflozin works the same way as empagliflozin — removing surplus glucose through the urine — and is used across the same three areas: type 2 diabetes, heart failure and chronic kidney disease. The same two safety points apply.
Type 2 diabetes, chronic heart failure and chronic kidney disease. In heart failure and kidney disease it is prescribed whether or not you have diabetes.
Modest weight loss and a small blood pressure reduction are common alongside its main effect.
Once daily, with or without food. Morning suits most people since it increases urine output.
Keep your fluid intake up, especially in hot weather. If you also take a diuretic, be alert to dizziness on standing.
Diabetic ketoacidosis can occur with normal or only mildly raised blood glucose on SGLT2 inhibitors. Get urgent help for nausea and vomiting, stomach pain, excessive thirst, fast or deep breathing, confusion, unusual tiredness or sweet-smelling breath — and say that you take an SGLT2 inhibitor.
Genital thrush and urinary tract infections are considerably more common because of the sugar in the urine. Wash and dry the area daily, and come to us early rather than waiting it out.
Not used in pregnancy or breastfeeding. Tell your team if you are planning a pregnancy.
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