Lyng Pharmacy
Medicines A–Z · H2 receptor antagonist

Famotidine

An H2 blocker for stomach acid · Written by the Lyng Pharmacy team, based on NHS and BNF guidance · Updated August 2026
Also sold asPepcid
Type of medicineH2 receptor antagonist
Available asTablets
How you get itPharmacy and prescription

Famotidine reduces stomach acid production, less powerfully than omeprazole but faster to act. It became the main H2 blocker in the UK after ranitidine was withdrawn in 2019, and it suits people who need more than an antacid but not a full PPI.

What it is used for

Heartburn, acid reflux and indigestion, and treating and preventing stomach and duodenal ulcers.

It works within about an hour and lasts up to twelve, which sits between an antacid (minutes, short-lived) and a PPI (days to full effect, longest lasting).

How to take it

Once or twice daily, with or without food. For predictable evening symptoms, a dose before your evening meal or at bedtime works well.

Pharmacy supply is intended for short-term use — up to two weeks. If you need it for longer, see your GP.

Side effects and when to see a doctor

Generally well tolerated. Headache, dizziness, constipation or diarrhoea are the more common effects.

See your GP rather than self-treating if you have difficulty or pain swallowing, unintentional weight loss, vomiting blood or coffee-ground vomit, black tarry stools, persistent vomiting, or new symptoms starting over the age of 55.

Tell us if you take other medicines — reducing stomach acid can affect the absorption of some, including certain antifungals and HIV medicines.

Always read the label. This page is general information, not advice for your situation. Doses, warnings and interactions differ between products and between people. Check the leaflet inside your medicine, and ask our pharmacist if anything is unclear — that conversation is free and takes two minutes.

Questions about Famotidine?

1 Lyng Lane, West Bromwich B70 7RW · Mon–Fri 8:30am–6pm, Sat 9am–1pm · 0121 500 5756

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Frequently asked questions

Is famotidine as strong as omeprazole?
No — it reduces acid less powerfully, but works faster. It sits between antacids and PPIs.
What happened to ranitidine?
Ranitidine was withdrawn worldwide in 2019 after impurity concerns. Famotidine is the H2 blocker used in its place.
How long can I take famotidine from a pharmacy?
Up to about two weeks. If you need it longer, see your GP.
When should heartburn be checked by a GP?
Difficulty swallowing, weight loss, vomiting blood, black stools, or first symptoms over 55 all need medical assessment.

Related pages

Omeprazole →Gaviscon and alginates →Indigestion and heartburn →All medicines A–Z →

More from Lyng Pharmacy

Order a repeat prescription →Pharmacy First — NHS treatment without a GP →Free medicine review →Contact us & opening hours →
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