Famotidine reduces stomach acid production, less powerfully than omeprazole but faster to act. It became the main H2 blocker in the UK after ranitidine was withdrawn in 2019, and it suits people who need more than an antacid but not a full PPI.
Heartburn, acid reflux and indigestion, and treating and preventing stomach and duodenal ulcers.
It works within about an hour and lasts up to twelve, which sits between an antacid (minutes, short-lived) and a PPI (days to full effect, longest lasting).
Once or twice daily, with or without food. For predictable evening symptoms, a dose before your evening meal or at bedtime works well.
Pharmacy supply is intended for short-term use — up to two weeks. If you need it for longer, see your GP.
Generally well tolerated. Headache, dizziness, constipation or diarrhoea are the more common effects.
See your GP rather than self-treating if you have difficulty or pain swallowing, unintentional weight loss, vomiting blood or coffee-ground vomit, black tarry stools, persistent vomiting, or new symptoms starting over the age of 55.
Tell us if you take other medicines — reducing stomach acid can affect the absorption of some, including certain antifungals and HIV medicines.
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