Lyng Pharmacy
Medicines A–Z · Proton pump inhibitor (reduces stomach acid)

Lansoprazole

Also sold as Zoton FasTab · Written by the Lyng Pharmacy team, based on NHS and BNF guidance · Updated August 2026
Also sold asZoton FasTab
Type of medicineProton pump inhibitor (reduces stomach acid)
Available asCapsules, orodispersible tablets
How you get itPrescription only

Lansoprazole belongs to the same family as omeprazole and does essentially the same job — reducing acid production at source. Which of the two you end up on is often a matter of what your prescriber chose or what interacts least with your other medicines.

What it is used for

Lansoprazole treats acid reflux and gastro-oesophageal reflux disease, indigestion, and stomach and duodenal ulcers. It is used to protect the stomach in people taking long-term anti-inflammatories, and forms part of the eradication treatment for Helicobacter pylori alongside antibiotics.

How to take it

Usually once daily in the morning, at least 30 minutes before food. Swallow capsules whole.

Orodispersible tablets are placed on the tongue and allowed to dissolve, or dispersed in a little water — useful if swallowing capsules is difficult. Do not chew or crush them.

If you are taking it twice a day, the second dose is usually in the evening. Take it consistently rather than only on bad days; these medicines work by keeping acid production low.

Side effects

Headache, nausea, diarrhoea, constipation, wind and stomach pain are the common ones and often settle within a week or two.

Get medical advice promptly for severe or persistent diarrhoea, unexplained muscle cramps or weakness, a rash, or yellowing of the eyes or skin.

Long-term use can affect absorption of vitamin B12 and magnesium and carries a small increase in risk of certain gut infections — so it is worth having repeat prescriptions reviewed periodically rather than continued indefinitely by default.

Interactions

Tell your prescriber if you take methotrexate, digoxin, certain antifungals or HIV medicines, or clopidogrel. Lansoprazole is generally considered to interact less with clopidogrel than omeprazole, which is one reason it is sometimes chosen.

Always read the label. This page is general information, not advice for your situation. Doses, warnings and interactions differ between products and between people. Check the leaflet inside your medicine, and ask our pharmacist if anything is unclear — that conversation is free and takes two minutes.

Questions about Lansoprazole?

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Frequently asked questions

Is lansoprazole the same as omeprazole?
They are in the same family and work the same way. Which one you are prescribed usually comes down to prescriber preference and how each interacts with your other medicines.
When should I take lansoprazole?
Usually once a day in the morning, at least 30 minutes before food, swallowed whole.
Can I stop lansoprazole suddenly?
Speak to your GP first. Symptoms can rebound if it is stopped abruptly after long-term use, and stepping down gradually often works better.
Can I take lansoprazole with anti-inflammatories?
Yes — it is frequently prescribed alongside them specifically to protect the stomach.

Related pages

Omeprazole →Naproxen →Indigestion and heartburn →All medicines A–Z →

More from Lyng Pharmacy

Order a repeat prescription →Pharmacy First — NHS treatment without a GP →Free medicine review →Contact us & opening hours →
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