Lyng Pharmacy
Medicines A–Z · Anti-diarrhoeal

Loperamide

Also sold as Imodium · Written by the Lyng Pharmacy team, based on NHS and BNF guidance · Updated August 2026
Also sold asImodium
Type of medicineAnti-diarrhoeal
Available asCapsules, tablets, melt-in-the-mouth tablets, liquid
How you get itGeneral sale and pharmacy; also on prescription

Loperamide slows the gut down and reduces how often you need the toilet. For ordinary short-lived diarrhoea in an adult it is genuinely useful. In a few situations it is the wrong thing entirely, and at high doses it is dangerous — both worth knowing before reaching for it.

When it is appropriate

Short-term diarrhoea in an adult with no fever, no blood in the stool and no severe abdominal pain — the classic upset stomach, or travellers’ diarrhoea where you need to get through a journey.

It treats the symptom, not the cause. Rehydration is the treatment that always matters: plenty of fluid in small frequent sips, and oral rehydration sachets if symptoms are heavy or the person is very young, elderly or frail.

When not to take it

Do not take loperamide if you have blood or mucus in your stool, a high temperature, or severe abdominal pain. These can point to an infection that the body needs to clear rather than trap.

Also avoid or check first if you:

How to take it

The usual adult approach is two capsules first, then one after each loose stool, up to a maximum of six in 24 hours for over-the-counter use. Follow the specific product label.

Do not use it for more than 48 hours without medical advice. If diarrhoea persists beyond that, it needs assessing.

Never exceed the stated dose. Very high doses of loperamide can cause dangerous heart rhythm problems, including cardiac arrest. This is not a medicine where taking extra helps.

Side effects

Constipation, wind, headache, nausea and dizziness are the common ones. Constipation after a bout of diarrhoea is normal and usually short-lived.

Get medical help for severe stomach pain or a swollen abdomen, no bowel movement combined with ongoing pain, or any fainting, palpitations or irregular heartbeat.

Always read the label. This page is general information, not advice for your situation. Doses, warnings and interactions differ between products and between people. Check the leaflet inside your medicine, and ask our pharmacist if anything is unclear — that conversation is free and takes two minutes.

Questions about Loperamide?

1 Lyng Lane, West Bromwich B70 7RW · Mon–Fri 8:30am–6pm, Sat 9am–1pm · 0121 500 5756

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Frequently asked questions

When should I not take loperamide?
Avoid it if you have blood or mucus in your stool, a high temperature, or severe abdominal pain — and if you are under 12, or have inflammatory bowel disease, check first.
How long can I take loperamide?
No more than 48 hours without medical advice. Diarrhoea lasting longer than that needs assessing.
Is it dangerous to take extra loperamide?
Yes. Very high doses can cause serious heart rhythm problems. Never exceed the stated dose.
Should I take loperamide or rehydration sachets?
Rehydration matters most — it is the treatment that prevents harm. Loperamide only reduces the symptom, and is optional.

Related pages

Diarrhoea →When loperamide helps and when it does not →All medicines A–Z →

More from Lyng Pharmacy

Order a repeat prescription →Pharmacy First — NHS treatment without a GP →Free medicine review →Contact us & opening hours →
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