Losartan works in a very similar way to ACE inhibitors such as ramipril, but without the dry cough that affects around one in ten people on those. That is the most common reason people are switched onto it.
High blood pressure, heart failure, protecting the kidneys in type 2 diabetes, and reducing the risk of stroke in people with high blood pressure and thickening of the heart muscle.
Once daily, with or without food, at the same time each day. It may take three to six weeks to reach its full blood-pressure-lowering effect.
You will usually have blood tests to check kidney function and potassium a week or two after starting or increasing the dose, and periodically after that.
Do not stop it because your readings have normalised — they are normal because of the tablet.
Dizziness, headache and tiredness are the common ones, particularly in the first days. Get up slowly from sitting or lying.
Losartan can raise potassium — avoid potassium-based salt substitutes, and tell your prescriber about potassium supplements.
Get urgent help for swelling of the face, lips, tongue or throat, or difficulty breathing.
Sartans must not be taken in pregnancy. Speak to your GP promptly if you are pregnant or planning a pregnancy.
Tell your prescriber about anti-inflammatories such as ibuprofen, lithium, and other blood pressure medicines.
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