Lyng Pharmacy
Medicines A–Z · Antibiotic (urinary)

Nitrofurantoin

Also sold as Macrobid · Written by the Lyng Pharmacy team, based on NHS and BNF guidance · Updated August 2026
Also sold asMacrobid, Macrodantin
Type of medicineAntibiotic (urinary)
Available asCapsules, tablets, oral suspension
How you get itPrescription only, including via Pharmacy First

Nitrofurantoin is the usual first-choice antibiotic for an uncomplicated urinary tract infection, because it concentrates in the urine where the infection is. For that same reason it is no use for infections anywhere else in the body.

What it is used for

Uncomplicated lower urinary tract infections — cystitis. It is also used at a low dose to prevent recurrent UTIs in some people.

At Lyng Pharmacy we can assess women aged 16 to 64 with an uncomplicated UTI under the Pharmacy First service and supply treatment where appropriate, without a GP appointment.

How to take it

A typical treatment course is three days for women, though your prescriber may advise longer. Take it with food or a glass of milk — this improves absorption and reduces nausea considerably.

Space doses evenly through the day and finish the course even if symptoms settle after a day or two.

Drink plenty of water throughout.

Who it is not suitable for

It can be used earlier in pregnancy where appropriate. Tell your prescriber if you are pregnant or might be.

Side effects

Nausea, loss of appetite, headache and diarrhoea are the common ones, and taking it with food helps. Your urine may turn dark yellow or brown, which is harmless and expected.

Get medical advice promptly for:

When a UTI needs a doctor rather than a pharmacy

Contact your GP or NHS 111 if you have back or side pain, a high temperature, shivering, nausea and vomiting, blood in the urine, or if symptoms are not improving after 48 hours of treatment. Those can point to a kidney infection, which needs different management. UTIs in men, in pregnancy, in children, and in anyone with a catheter also need medical assessment.

Always read the label. This page is general information, not advice for your situation. Doses, warnings and interactions differ between products and between people. Check the leaflet inside your medicine, and ask our pharmacist if anything is unclear — that conversation is free and takes two minutes.

Questions about Nitrofurantoin?

1 Lyng Lane, West Bromwich B70 7RW · Mon–Fri 8:30am–6pm, Sat 9am–1pm · 0121 500 5756

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Frequently asked questions

Why has my urine turned brown on nitrofurantoin?
This is a harmless and expected effect of the medicine, not a sign of a problem.
Should I take nitrofurantoin with food?
Yes — with food or a glass of milk. It improves absorption and substantially reduces nausea.
Can I get UTI treatment without seeing a GP?
Women aged 16 to 64 with an uncomplicated UTI can be assessed at the pharmacy under Pharmacy First, and treated where appropriate.
When is a UTI more serious?
Back or side pain, high temperature, shivering, vomiting or blood in the urine can indicate a kidney infection and need medical assessment the same day.

Related pages

Urinary tract infection →UTI treatment without a GP appointment →Pharmacy First →All medicines A–Z →

More from Lyng Pharmacy

Order a repeat prescription →Pharmacy First — NHS treatment without a GP →Free medicine review →Contact us & opening hours →
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