Lyng Pharmacy
Medicines A–Z · Anticonvulsant / nerve pain medicine

Pregabalin

For nerve pain, epilepsy and anxiety · Written by the Lyng Pharmacy team, based on NHS and BNF guidance · Updated August 2026
Also sold asLyrica
Type of medicineAnticonvulsant / nerve pain medicine
Available asCapsules, oral solution
How you get itPrescription only — a controlled drug

Pregabalin is used for nerve pain, epilepsy and generalised anxiety disorder. Like gabapentin it is a controlled drug, it is started low and increased gradually, and it must never be stopped abruptly.

What it is used for

Nerve pain — diabetic neuropathy, post-shingles pain, sciatica — as an add-on treatment for some epilepsy, and for generalised anxiety disorder.

It has to be taken regularly to build up an effect; it is not an as-needed medicine.

How to take it

Usually two or three times a day, with or without food, at evenly spaced intervals. The dose is increased in steps over days or weeks to let side effects settle.

Allow several weeks at an effective dose to judge whether it is helping. If it is not, it should be reduced and stopped rather than continued.

Never stop pregabalin abruptly. Withdrawal can cause anxiety, difficulty sleeping, nausea, sweating and pain, and can trigger seizures in people taking it for epilepsy. Reduce gradually with your GP.

Side effects and safety

Drowsiness, dizziness, unsteadiness, blurred vision, weight gain, swollen ankles and dry mouth are common. Do not drive or use machinery until you know how it affects you — driving while impaired is an offence.

Contact your doctor for mood changes or thoughts of harming yourself — Samaritans are on 116 123, free, at any hour — or for breathing difficulties, or swelling of the face or throat.

Pregabalin with opioid painkillers significantly increases the risk of serious breathing problems, particularly in older people and those with lung disease. Tell your prescriber everything you take, including anything bought over the counter.

Alcohol adds substantially to drowsiness. As a controlled drug there are rules about prescription validity and travelling abroad — ask us before a trip.

Always read the label. This page is general information, not advice for your situation. Doses, warnings and interactions differ between products and between people. Check the leaflet inside your medicine, and ask our pharmacist if anything is unclear — that conversation is free and takes two minutes.

Questions about Pregabalin?

1 Lyng Lane, West Bromwich B70 7RW · Mon–Fri 8:30am–6pm, Sat 9am–1pm · 0121 500 5756

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Frequently asked questions

Can I stop pregabalin suddenly?
No. Withdrawal can cause anxiety, insomnia, nausea and pain, and can trigger seizures in people with epilepsy. Reduce gradually with your GP.
Is pregabalin a controlled drug?
Yes. That affects prescription validity and taking it abroad — ask us before travelling.
Can I drive on pregabalin?
Not until you know how it affects you. It commonly causes drowsiness and dizziness, and driving while impaired is an offence.
Is it safe to take pregabalin with codeine or morphine?
The combination significantly increases the risk of serious breathing problems. Your prescriber needs to know everything you take.

Related pages

Gabapentin →Amitriptyline →Shingles →All medicines A–Z →

More from Lyng Pharmacy

Order a repeat prescription →Pharmacy First — NHS treatment without a GP →Free medicine review →Contact us & opening hours →
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