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Headaches: When Painkillers Are the Problem, Not the Cure

By the Lyng Pharmacy team · Based on NHS and BNF guidance · August 2026 · 3 min read
Man outdoors holding his hand to his forehead with a headache
Taking painkillers for headache on more than ten to fifteen days a month can start causing the very headaches you are treating.

There is a trap that catches a surprising number of people, and it is one of the more satisfying things to spot at the counter: a headache that has become daily, treated faithfully with painkillers every morning, where the painkillers themselves are now causing it. It is called medication-overuse headache, and the way out is counterintuitive.

Telling the common types apart

Tension-type headache is the everyday one — a dull, pressing, band-like tightness on both sides, mild to moderate, not made worse by moving about. No nausea, no visual disturbance.

Migraine is usually one-sided, throbbing, moderate to severe, and made worse by ordinary movement. It often comes with nausea and a strong dislike of light or noise, and can last from four hours to three days. Around a third of people get an aura first — typically visual zigzags or blind spots lasting up to an hour.

Cluster headache is far less common but unmistakable: excruciating pain around one eye, coming in bouts, often with a red watering eye and blocked nostril on the same side. It needs a GP.

Medication-overuse headache

If you take painkillers for headache on ten or more days a month — or fifteen or more for simple paracetamol or ibuprofen — and have done so for over three months, the medication can start driving the headaches. It is most common with codeine-containing painkillers and triptans.

The pattern is telling: headache present most days, often there on waking, and briefly relieved by a painkiller that then wears off into the next one.

The treatment is to stop the offending painkiller. Headaches typically worsen for one to two weeks before improving, and many people are substantially better by four to eight weeks. It is not comfortable, and it is worth doing with support — come and talk to us, or your GP, rather than attempting it blind, particularly if codeine is involved.

Treating headaches well

Headaches that need urgent assessment

Call 999 or go to A&E for a headache that comes on suddenly and is extremely severe — a thunderclap headache reaching maximum intensity within seconds to a minute. Also seek urgent help for headache with:

Headaches every day?

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Frequently asked questions

Can painkillers cause headaches?
Yes. Taking painkillers for headache on ten or more days a month — fifteen for paracetamol or ibuprofen — for over three months can cause medication-overuse headache. Stopping the painkiller is the treatment.
How do I tell a migraine from a tension headache?
Migraine is usually one-sided, throbbing, worsened by movement and often comes with nausea or light sensitivity. Tension headache is a dull band-like pressure on both sides without those features.
When is a headache an emergency?
A sudden extremely severe headache peaking within a minute, or headache with stiff neck, fever, non-fading rash, confusion, weakness or visual loss, needs emergency assessment.
What helps prevent headaches?
Regular sleep, regular meals, good hydration, steady caffeine intake and managing stress prevent a great many. A headache diary usually reveals personal triggers within a few weeks.

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