Lisinopril is an ACE inhibitor, used much like ramipril for blood pressure, heart failure and kidney protection. The same two practical points apply: it commonly causes a dry cough, and it should be paused during dehydrating illness.
Once daily, at the same time each day, with or without food. The first dose is often taken at bedtime because it can cause dizziness.
Blood tests for kidney function and potassium are done a week or two after starting or increasing the dose, and periodically after that.
Do not stop it because your blood pressure readings have normalised — they are normal because of the tablet.
Around one in ten people develop a persistent dry, tickly cough. It is harmless but irritating and does not respond to cough medicine. Switching to a sartan such as losartan usually resolves it — tell your GP rather than putting up with it.
Dizziness, headache and tiredness are common early on and often settle. Get up slowly from sitting or lying.
Pause lisinopril if you become dehydrated from vomiting, diarrhoea or fever with heavy sweating, and restart when eating and drinking normally. Ask us for a sick day rules card.
Avoid potassium-based salt substitutes. Tell your prescriber about anti-inflammatories, lithium and potassium supplements.
ACE inhibitors must not be taken in pregnancy. Speak to your GP promptly if you are pregnant or planning a pregnancy.
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