Levetiracetam is a widely used antiepileptic with few drug interactions, which is one of its main advantages. Its most important side effect is not physical — it is the effect it can have on mood and behaviour.
Usually twice daily, with or without food, at roughly twelve-hour intervals. Swallow tablets whole with water.
Doses are increased gradually. Take it consistently at the same times — missed doses are a common cause of breakthrough seizures.
Irritability, aggression, agitation, anxiety, low mood and, less commonly, thoughts of self-harm can occur — in adults and children. These are among the commonest reasons levetiracetam is changed, and they are worth reporting early rather than tolerating.
Tell your specialist about any noticeable change in mood or behaviour, in yourself or in your child. If you need to talk to someone right now, Samaritans are on 116 123, free, at any hour.
Common side effects: drowsiness, tiredness, dizziness, headache and cold-like symptoms. Do not drive until you know how it affects you, and note that driving after a seizure has its own DVLA rules.
Levetiracetam has few interactions, which is why it suits people on several medicines. Alcohol still adds to drowsiness.
Blood levels are not routinely monitored. Discuss pregnancy plans with your specialist — levetiracetam is among the preferred options, but doses often need adjusting during pregnancy.
Stay on the same brand where possible.
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